2013Chinese Journal of AIDS & STDRequires access

Comparison of rash reactions associated with Efavirenz and Nevirapine among AIDS patients

Huiqin Li

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Abstract

Objective To compare the proportion that AIDS patients taking efavirenz or nevirapine suffered from rash reaction.Method To retrospectively collect and analyze the records of 1 034AIDS patients taking either efavirenz or nevirapine.Results The proportions of rash reaction associated with efavirenz and nevirapine were 9.26%(45/486)and 9.85%(54/548),respectively(P0.05),the average onset time of rash reaction was(13.20± 3.15)days and(18.83±6.68)days,respectively(P0.01).Conclusion Clinicians may provide timely diagnosis and treatment towards rash reaction according to prescription and onset time among AIDS patients.

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What this paper is about

Objective To compare the proportion that AIDS patients taking efavirenz or nevirapine suffered from rash reaction.Method To retrospectively collect and analyze the records of 1 034AIDS patients taking either efavirenz or nevirapine.Results The proportions of rash reaction associated with efavirenz and nevirapine were 9.26%(45/486)and 9.85%(54/548),respectively(P0.05),the average onset time of rash reaction was(13.20± 3.15)days and(18.83±6.68)days,respectively(P0.01).Conclusion Clinicians may provide timely diagnosis and treatment towards rash reaction according to prescription and onset time among AIDS patients.

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Available abstract

Objective To compare the proportion that AIDS patients taking efavirenz or nevirapine suffered from rash reaction.Method To retrospectively collect and analyze the records of 1 034AIDS patients taking either efavirenz or nevirapine.Results The proportions of rash reaction associated with efavirenz and nevirapine were 9.26%(45/486)and 9.85%(54/548),respectively(P0.05),the average onset time of rash reaction was(13.20± 3.15)days and(18.83±6.68)days,respectively(P0.01).Conclusion Clinicians may provide timely diagnosis and treatment towards rash reaction according to prescription and onset time among AIDS patients.

Key concepts: Nevirapine, Efavirenz, Rash, Medicine, Dermatology, Medical prescription, Human immunodeficiency virus (HIV), Pediatrics

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