Analysis of 57372 cases on cervical liquid cytology

Objective:To evaluate the sensitivity and clinical value of liquid-based cytology in the screening of cervical cancer,investigate the relative factors of cervical disease.Methods:57 372 cases of liquid-based cytology were collected and observed,when atypical squamous cell of undetermined significance (ASC-US) or above of the cases were diagnosed by cytology,they underwent biopsy of colposcopy and compared with the biopsy diagnosis.Results:Among the 57 372 cases,49 052 cases (85.5%) were negative for intraepithelial lesion or malignancy (NILM),3 848 cases (6.71%) were ASC,3 862 caes (6.73%) were low-grade intraepithelial lesion (LSIL),470 cases (0.82%) were high-grade intraepithelial lesion (HSIL),46 cases (0.09%) were squamous cell carcinoma (SCC),72 cases (0.13%) were atypical glandular cell of undetermined significance (AGC),6 cases (0.02%) were adenocarcinoma (AC).Compared with the biopsy,the cytology was able to detect 100% (46/46) of SCC,100% (6/6) of AC,94.42% (186/197) of HSIL and 80.99% (903/1 115) of LSIL.The average ages of CIN Ⅰ,C1N Ⅱ,CIN Ⅲ,SCC and AC were (33.30±13.28),(35.30±7.83),(72.25±7.61),(45.61±6.73) and (42.67±10.13) years.Conclusion:The cervical lesion,especially the precancer lesion is a younger tendency in age of occurrence of the disease. Liquid-based cytology can detect cervical lesion effectively,coped with colposcopy test,it can decrease the incidence rate and death rate of the cervical cancer.