Effect of Surface Properties on the Biocompatibility of Polyurethane

Polyurethane(PU) has been widely used biomedical material with good stability,excellent mechanical properties and reasonable biocompatibility due to its specific micro-phase separation structure.However,its unsatisfactory blood compatibility results in limitation of application in the biomaterial fields.As far as the dependence of biocompatibility on surface properties of materials is concerned,surface modification has been recognized a preferable way to improve the biocompatibility for biomaterials.In view of many methods applied to modify the surface of polyurethane,the bioactive molecules modified surface through chemical modification has attracted a great of interest.In the present article the approaches of modification to improve the biocompatibility of polyurethane were briefly summarized,and the relationship between polyurethane surface properties and biocompatibility was also discussed.