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2009•Chinese Journal of Modern Drug ApplicationRequires access

The clinical study of the relationship between cardiomyocyte injury markers and acute myocardial infarction

Liu Chang-jian

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Abstract

Objective To investigate the relationship between cardiomyocyte injury markers and acute myocardial infarction(AMI).Methods The serum level of HS-CRP,SF,β2 MG and cTnI were detected and analysized in patients with AMI.Results ①The serum level of HS-CRP,SF,β2 MG and cTnI were significantly higher in patients with AMI than in control groups.The serum level of HS-CRP,SF,β2 MG and cTnI were significantly higher in patients with unstable angina pectoris(UAP)than in control groups.② The specificity of serum cTnI was significantly higher than HS-CRP,SF and β2 MG in diagnosing AMI.The sensitivity of serum cTnI was significantly higher than HS-CRP,SF and β2 MG in patients who suffer from AMI over 9 hours.Conclusions The patients with AMI have high serum level of HS-CRP、SF、β2 MG and cTnI.The serum level of cTnI was a good marker in diagnosing or following patients with AMI.

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Objective To investigate the relationship between cardiomyocyte injury markers and acute myocardial infarction(AMI).Methods The serum level of HS-CRP,SF,β2 MG and cTnI were detected and analysized in patients with AMI.Results ①The serum level of HS-CRP,SF,β2 MG and cTnI were significantly higher in patients with AMI than in control groups.The serum level of HS-CRP,SF,β2 MG and cTnI were significantly higher in patients with unstable angina pectoris(UAP)than in control groups.② The specificity of serum cTnI was significantly higher than HS-CRP,SF and β2 MG in diagnosing AMI.The sensitivity of serum cTnI was significantly higher than HS-CRP,SF and β2 MG in patients who suffer from AMI over 9 hours.Conclusions The patients with AMI have high serum level of HS-CRP、SF、β2 MG and cTnI.The serum level of cTnI was a good marker in diagnosing or following patients with AMI.

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Available abstract

Objective To investigate the relationship between cardiomyocyte injury markers and acute myocardial infarction(AMI).Methods The serum level of HS-CRP,SF,β2 MG and cTnI were detected and analysized in patients with AMI.Results ①The serum level of HS-CRP,SF,β2 MG and cTnI were significantly higher in patients with AMI than in control groups.The serum level of HS-CRP,SF,β2 MG and cTnI were significantly higher in patients with unstable angina pectoris(UAP)than in control groups.② The specificity of serum cTnI was significantly higher than HS-CRP,SF and β2 MG in diagnosing AMI.The sensitivity of serum cTnI was significantly higher than HS-CRP,SF and β2 MG in patients who suffer from AMI over 9 hours.Conclusions The patients with AMI have high serum level of HS-CRP、SF、β2 MG and cTnI.The serum level of cTnI was a good marker in diagnosing or following patients with AMI.

Key concepts: Medicine, Troponin I, Myocardial infarction, Internal medicine, Unstable angina, Cardiology, C-reactive protein, Inflammation

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