2010•Fain kemikaruRequires access

α-Glucosidase Inhibitory Activity in vitro and vivo of Lindera Glauca(Sieblet Zucc) Blume

Wenyi Kang

Abstract

To investigate the yeast and the rat intestinal α-glucosidase inhibitory activity of Lindera glauca(Sieblet Zucc)Blume,in vitro and vivo.Its α-glucosidase inhibitory activity was assayed by the method of 96-microplates.The results showed that yeast α-glucosidase inhibitory activity of petroleum ether extracts(IC50=229.70 μg/mL),ethyl acetate extracts(IC50=259.10 μg/mL)and n-butanol extracts was lower than that of Acarbose(IC50=1 081.27 μg/mL)as positive control,and only ethyl acetate extracts(IC50=418.17 μg/mL)showed the rat intestinal α-glucosidase inhibitory activity.The IC50value of Acarbose could not be detected.The results indicated that all the extracts of L.glauca showed a better yeast α-glucosidase inhibitory activity and only ethyl acetate extracts showed a better rat intestinal α-glucosidase inhibitory activity.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Acarbose, Ethyl acetate, Chemistry, IC50, Inhibitory postsynaptic potential, In vivo, In vitro, Petroleum ether