2008Journal of Practical Medical TechniquesRequires access

Spinal anesthesia with sufentanil-bupivacaine in elderly patients

Baojiang Liu

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Abstract

Objective To evaluate the quality of anesthesia and side effect on elderly patients of spinal anesthesia with low dose sufentanil-bupivacaine.Methods Ninety patients(60~81 year,ASA Ⅰ~Ⅱ)undergoing spinal anesthesia were randomly divided into 3 groups(n=30):Group B1,B2 and BS.Group B1 received 15 mg bupivacaine;Group B2 re-ceived 10 mg bupivacaine;Group BS received 10 mg bupivacaine + 5 μg sufentanil.The volume was 3 ml in every group.SP,DP,HR,RR,BIS,SpO2,the degree and duration of motor and sensory blockade and the side effect were observed.Results ① SP/DP was significantly decreased in Group B1 than that in Group B2 and Group BS(P0.01)in 3,5,15,and 30 min after the injection.② The onset time of sensory blockade,highest sensory blockade level,the regression time of sensory blockade were obviously differentin Group B1,BS than that in Group B2(P0.05).③ The complete recovery time of motor nerve eblockade was obviously prolonged in Group B1 than that in Group B2,BS(P0.01)and the Bromage score was higher in Group B1 than that in Group B2,BS(P0.05).④ There were no significant differences in side effect among the three groups.The dosage of ephedrine was lower in Group BS and B2 than that in Group B1(P0.05).Conclu-sion Spinal anesthesia with low dose sufentanil-bupivacaine provided safe and effective anesthesia for elderly patients.

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Objective To evaluate the quality of anesthesia and side effect on elderly patients of spinal anesthesia with low dose sufentanil-bupivacaine.Methods Ninety patients(60~81 year,ASA Ⅰ~Ⅱ)undergoing spinal anesthesia were randomly divided into 3 groups(n=30):Group B1,B2 and BS.Group B1 received 15 mg bupivacaine;Group B2 re-ceived 10 mg bupivacaine;Group BS received 10 mg bupivacaine + 5 μg sufentanil.The volume was 3 ml in every group.SP,DP,HR,RR,BIS,SpO2,the degree and duration of motor and sensory blockade and the side effect were observed.Results ① SP/DP was significantly decreased in Group B1 than that in Group B2 and Group BS(P0.01)in 3,5,15,and 30 min after the injection.② The onset time of sensory blockade,highest sensory blockade level,the regression time of sensory blockade were obviously differentin Group B1,BS than that in Group B2(P0.05).③ The complete recovery time of motor nerve eblockade was obviously prolonged in Group B1 than that in Group B2,BS(P0.01)and the Bromage score was higher in Group B1 than that in Group B2,BS(P0.05).④ There were no significant differences in side effect among the three groups.The dosage of ephedrine was lower in Group BS and B2 than that in Group B1(P0.05).Conclu-sion Spinal anesthesia with low dose sufentanil-bupivacaine provided safe and effective anesthesia for elderly patients.

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Available abstract

Objective To evaluate the quality of anesthesia and side effect on elderly patients of spinal anesthesia with low dose sufentanil-bupivacaine.Methods Ninety patients(60~81 year,ASA Ⅰ~Ⅱ)undergoing spinal anesthesia were randomly divided into 3 groups(n=30):Group B1,B2 and BS.Group B1 received 15 mg bupivacaine;Group B2 re-ceived 10 mg bupivacaine;Group BS received 10 mg bupivacaine + 5 μg sufentanil.The volume was 3 ml in every group.SP,DP,HR,RR,BIS,SpO2,the degree and duration of motor and sensory blockade and the side effect were observed.Results ① SP/DP was significantly decreased in Group B1 than that in Group B2 and Group BS(P0.01)in 3,5,15,and 30 min after the injection.② The onset time of sensory blockade,highest sensory blockade level,the regression time of sensory blockade were obviously differentin Group B1,BS than that in Group B2(P0.05).③ The complete recovery time of motor nerve eblockade was obviously prolonged in Group B1 than that in Group B2,BS(P0.01)and the Bromage score was higher in Group B1 than that in Group B2,BS(P0.05).④ There were no significant differences in side effect among the three groups.The dosage of ephedrine was lower in Group BS and B2 than that in Group B1(P0.05).Conclu-sion Spinal anesthesia with low dose sufentanil-bupivacaine provided safe and effective anesthesia for elderly patients.

Key concepts: Medicine, Bupivacaine, Sufentanil, Anesthesia, Ephedrine, Blockade, Surgery, Internal medicine

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