2010•Chinese Medical Equipment JournalRequires access

Hydrogen Proton Magnetic Resonance Spectroscopy of Brain Diseases

Nan Jia

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Abstract

Objective To evaluate the hydrogen proton magnetic resonance spectroscopy(1H-MRS) in the diagnosis of brain diseases.Methods 1.5 Tesla MR scanner of GE Company was used,and single voxel technique was applied in 45 healthy subjects as control group and 115 patients presented with different brain lesions.The 1H-MRS metabolites waveform were evaluated,and the results were analyzed.Results The values of NAA,Cho,Cr and Lac,Lip and NAA/Cho as well as Cho/Cr from the patients showed a statistical difference to the control group,with P not more than 0.05.Conclusion The 1H-MRS results of lesions in the brain disease show statistical differences,and when combined with conventional MRI can contribute to a confident diagnosis.

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What this paper is about

Objective To evaluate the hydrogen proton magnetic resonance spectroscopy(1H-MRS) in the diagnosis of brain diseases.Methods 1.5 Tesla MR scanner of GE Company was used,and single voxel technique was applied in 45 healthy subjects as control group and 115 patients presented with different brain lesions.The 1H-MRS metabolites waveform were evaluated,and the results were analyzed.Results The values of NAA,Cho,Cr and Lac,Lip and NAA/Cho as well as Cho/Cr from the patients showed a statistical difference to the control group,with P not more than 0.05.Conclusion The 1H-MRS results of lesions in the brain disease show statistical differences,and when combined with conventional MRI can contribute to a confident diagnosis.

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Available abstract

Objective To evaluate the hydrogen proton magnetic resonance spectroscopy(1H-MRS) in the diagnosis of brain diseases.Methods 1.5 Tesla MR scanner of GE Company was used,and single voxel technique was applied in 45 healthy subjects as control group and 115 patients presented with different brain lesions.The 1H-MRS metabolites waveform were evaluated,and the results were analyzed.Results The values of NAA,Cho,Cr and Lac,Lip and NAA/Cho as well as Cho/Cr from the patients showed a statistical difference to the control group,with P not more than 0.05.Conclusion The 1H-MRS results of lesions in the brain disease show statistical differences,and when combined with conventional MRI can contribute to a confident diagnosis.

Key concepts: Proton magnetic resonance, Nuclear magnetic resonance, Magnetic resonance imaging, Nuclear medicine, Proton, Voxel, Spectroscopy, Nuclear magnetic resonance spectroscopy

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