Clinic study in the treatment of acute myocardial infarction with post thrombolysis percutaneous coronary intervention

Objective To evaluate the effects and safety of the treatment on acute myocardial infarction (AMI) with post thrombolysis (PCI) Methods Thirty five patients with AMI was arranged to group A (post thrombolysis PCI) and group B (primary PCI)according to whether they had a treatment with thrombolysis before they had a PCI procedures And observed the time from AMI onset to the beginning of PCI percutaneous coronary intervention the TIMI grade in coronary angiography,the time from coronary angiography to the dilating of balloon,the rate of reperfusion induced arrhymias during PCI,the rate of angina pectoris post PCI,the Killips grade before and after PCI procedures,and evaluated the LVEF four weeks after PCI with two dimensional echocardiography assessment and all the complications The paraments and clinical features were analyzed retrospectively Results The time from AMI onset tothe beginning of PCI of group A was longer than that of group B (6 63±093 hours vs 5 28±0 67 hours,P 0 05),the TIMI grade 2 and 3 of group A was better thn that of group B in coronary angiographic assessment (55%vs 20%,P 0 05) There was no significant difference between group A and B in the time from coronary angiography to the dilating of balloon (17 5min vs 18 5min,P 0 05) and also the rate of angina pectoris post PCI of group A and B(P 0 05) But the rate of reperfusion induced arrhymias of group A was lower than that of group B (P 0 05) There was no significant difference between group A and group B in Killips grade before PCI (P 0 05) and in LVEF four weeks after PCI assessed with echocardiography (0 62±0 04 vs 0 63±0 04,P 0 05) Both groups had no bleeding complications Conclusions The patients with AMI should treated with thrombolysis as ealier as possible;and the treatment of these patient with post thrombolysis PCI is effect and satety