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Therapeutic Effect of rhKD/APP var on Acute Necrosis Pancreatitis in Rats

Renren Sun

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Abstract

Objective To determine the therapeutic effect of rhKD/APP var on acute necrosis pancreatitis in rats.Methods Acute necrosis pancreatitis was induced by injections of odium taurocholate into the main pancreaticduct of rats.Serum amylase and lipase activities of the rats were assayed and histopathological changes were observed after treatment with rhKD/APP var.Results rhKD/APP var inhibited the serum amylase and lipase activities remarkably and ameliorated the histopathological changes of the pancreas.Conclusion rhKD/APP var can suppress pathogenesis of the acute necrosis pancreatitis in rats.

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What this paper is about

Objective To determine the therapeutic effect of rhKD/APP var on acute necrosis pancreatitis in rats.Methods Acute necrosis pancreatitis was induced by injections of odium taurocholate into the main pancreaticduct of rats.Serum amylase and lipase activities of the rats were assayed and histopathological changes were observed after treatment with rhKD/APP var.Results rhKD/APP var inhibited the serum amylase and lipase activities remarkably and ameliorated the histopathological changes of the pancreas.Conclusion rhKD/APP var can suppress pathogenesis of the acute necrosis pancreatitis in rats.

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Available abstract

Objective To determine the therapeutic effect of rhKD/APP var on acute necrosis pancreatitis in rats.Methods Acute necrosis pancreatitis was induced by injections of odium taurocholate into the main pancreaticduct of rats.Serum amylase and lipase activities of the rats were assayed and histopathological changes were observed after treatment with rhKD/APP var.Results rhKD/APP var inhibited the serum amylase and lipase activities remarkably and ameliorated the histopathological changes of the pancreas.Conclusion rhKD/APP var can suppress pathogenesis of the acute necrosis pancreatitis in rats.

Key concepts: Necrosis, Acute pancreatitis, Lipase, Amylase, Pancreatitis, Pathogenesis, Medicine, Pancreas

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