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Advancement in the study of mechanism of microRNA in metastasis of colorectal cancer

Zongyou Chen

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Abstract

The metastasis of tumor cells is a pathological process that comprises multiple factors.microRNA is one of the important parts taking part in the regulation of the process.Complication of metastasis is the major cause of death in colorectal cancer(CRC).Nowadays research of microRNA in metastisis of CRC still remains inefficient and anti-apoptotis,epithelial-mesenchymal transition,gain of invation as well as angiogenesis is known to be the major regulation method,positive or negative.This review explores recent development in the role of microRNA and its mechanism of CRC metastases which may provide new insights that could be of therapeutic consequence.

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What this paper is about

The metastasis of tumor cells is a pathological process that comprises multiple factors.microRNA is one of the important parts taking part in the regulation of the process.Complication of metastasis is the major cause of death in colorectal cancer(CRC).Nowadays research of microRNA in metastisis of CRC still remains inefficient and anti-apoptotis,epithelial-mesenchymal transition,gain of invation as well as angiogenesis is known to be the major regulation method,positive or negative.This review explores recent development in the role of microRNA and its mechanism of CRC metastases which may provide new insights that could be of therapeutic consequence.

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Available abstract

The metastasis of tumor cells is a pathological process that comprises multiple factors.microRNA is one of the important parts taking part in the regulation of the process.Complication of metastasis is the major cause of death in colorectal cancer(CRC).Nowadays research of microRNA in metastisis of CRC still remains inefficient and anti-apoptotis,epithelial-mesenchymal transition,gain of invation as well as angiogenesis is known to be the major regulation method,positive or negative.This review explores recent development in the role of microRNA and its mechanism of CRC metastases which may provide new insights that could be of therapeutic consequence.

Key concepts: Metastasis, microRNA, Colorectal cancer, Angiogenesis, Mechanism (biology), Epithelial–mesenchymal transition, Pathological, Cancer

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