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2006•Journal of Clinical Internal MedicineRequires access

The effect of on-line hemodiafiltration on hypertension in patients with end-stage renal disease

Ruijun Guo

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Abstract

Objective To evaluate the clinical effect of hemodiafiltration on end-stage renal disease with hypertension and the patients' tolerance to this treatment.Methods Ten patients with serious hypertension received hemodiafiltration (HDF) during maintenance hemodialysis (HD).Blood urea nitrogen(Bun),creatinine (Cr),phosphorus (P),parathyroid hormone (PTH),MAP,periplasmal rennin activity (PRA) and angiotonin II (ATⅡ) were examined before and 5 months after hemodiafiltration.Other ten patients received standard HD as control.Results No significantly difference was found in the clearances of Cr,Bun and PRA between HDF and HD patients;But the PTH,MAP and ATⅡ in HDF group elevated more than those in HD group,so compared with HD,HDF was more effective on the patients with serious hypertension during maintenance hemodialysis.Conclusion HDF is a high effective dialysis method on the ESRD patients with serious hypertension. [

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Objective To evaluate the clinical effect of hemodiafiltration on end-stage renal disease with hypertension and the patients' tolerance to this treatment.Methods Ten patients with serious hypertension received hemodiafiltration (HDF) during maintenance hemodialysis (HD).Blood urea nitrogen(Bun),creatinine (Cr),phosphorus (P),parathyroid hormone (PTH),MAP,periplasmal rennin activity (PRA) and angiotonin II (ATⅡ) were examined before and 5 months after hemodiafiltration.Other ten patients received standard HD as control.Results No significantly difference was found in the clearances of Cr,Bun and PRA between HDF and HD patients;But the PTH,MAP and ATⅡ in HDF group elevated more than those in HD group,so compared with HD,HDF was more effective on the patients with serious hypertension during maintenance hemodialysis.Conclusion HDF is a high effective dialysis method on the ESRD patients with serious hypertension. [

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Available abstract

Objective To evaluate the clinical effect of hemodiafiltration on end-stage renal disease with hypertension and the patients' tolerance to this treatment.Methods Ten patients with serious hypertension received hemodiafiltration (HDF) during maintenance hemodialysis (HD).Blood urea nitrogen(Bun),creatinine (Cr),phosphorus (P),parathyroid hormone (PTH),MAP,periplasmal rennin activity (PRA) and angiotonin II (ATⅡ) were examined before and 5 months after hemodiafiltration.Other ten patients received standard HD as control.Results No significantly difference was found in the clearances of Cr,Bun and PRA between HDF and HD patients;But the PTH,MAP and ATⅡ in HDF group elevated more than those in HD group,so compared with HD,HDF was more effective on the patients with serious hypertension during maintenance hemodialysis.Conclusion HDF is a high effective dialysis method on the ESRD patients with serious hypertension. [

Key concepts: Medicine, Hemodialysis, Creatinine, End stage renal disease, Blood urea nitrogen, Parathyroid hormone, Dialysis, Internal medicine

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The effect of on-line hemodiafiltration on hypertension in patients with end-stage renal disease — Research Paper | ScholarLens