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Comparison of analgesic effects between naproxen and diclofenac in randomized controlled trials

Lao Zhi, Yang Hu, Xia Liu

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Abstract

Naproxen 2mL (0.2g) or diclofenac 2mL (50mg) was injected im to 170 patients with rheumatoid arthritis bid, for 14 d, and qd or bid to 70 women with dysmenorrhea and 72 patients with postoperative pain for randomized double-blind trials. Results showed no significant difference between the analgesic effects of the 2 drugs (P0. 05). Severe pain at the im site was complained by 43% and 42% of the patients after naproxen and diclofenac, respectively.

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What this paper is about

Naproxen 2mL (0.2g) or diclofenac 2mL (50mg) was injected im to 170 patients with rheumatoid arthritis bid, for 14 d, and qd or bid to 70 women with dysmenorrhea and 72 patients with postoperative pain for randomized double-blind trials. Results showed no significant difference between the analgesic effects of the 2 drugs (P0. 05). Severe pain at the im site was complained by 43% and 42% of the patients after naproxen and diclofenac, respectively.

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Available abstract

Naproxen 2mL (0.2g) or diclofenac 2mL (50mg) was injected im to 170 patients with rheumatoid arthritis bid, for 14 d, and qd or bid to 70 women with dysmenorrhea and 72 patients with postoperative pain for randomized double-blind trials. Results showed no significant difference between the analgesic effects of the 2 drugs (P0. 05). Severe pain at the im site was complained by 43% and 42% of the patients after naproxen and diclofenac, respectively.

Key concepts: Naproxen, Diclofenac, Analgesic, Medicine, Rheumatoid arthritis, Anesthesia, Randomized controlled trial, Single blind

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