2012Anhui Medical and Pharmaceutical JournalRequires access

Risk factors of low rectal anastomotic leakage

Su Jiang

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Abstract

Objective To investigate risk factors,prevention and treatment of postoperative anastomotic leakage in rectal cancer.Methods A total of 218 cases of low rectal anastomotic leakage were analyzed in risk factors.Conservative treatment and surgeries were used in patients with anastomotic leakage.Results Postoperative anastomotic leakage occurred in 19 patients(8.7%),conservative treatment in 17 cases and surgical treatment in 2 cases.There was a statistically significant difference in diabetes mellitus(P=0.019 6),serum albumin(P=0.003 1),anastomotic location(P=0.024 1).Logistic regression found that serum albumin level(OR=5.769,95% CI=1.751~23.712,P=0.003 5) was the most important risk factor,followed by diabetes,anastomotic location.Conclusion More attention should be paid to postoperative anastomotic leakage risk factors.Satisfactory preoperative preparation,grasping the main points of rectal cancer surgery were the keys to the prevention of anastomotic leakage.

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Objective To investigate risk factors,prevention and treatment of postoperative anastomotic leakage in rectal cancer.Methods A total of 218 cases of low rectal anastomotic leakage were analyzed in risk factors.Conservative treatment and surgeries were used in patients with anastomotic leakage.Results Postoperative anastomotic leakage occurred in 19 patients(8.7%),conservative treatment in 17 cases and surgical treatment in 2 cases.There was a statistically significant difference in diabetes mellitus(P=0.019 6),serum albumin(P=0.003 1),anastomotic location(P=0.024 1).Logistic regression found that serum albumin level(OR=5.769,95% CI=1.751~23.712,P=0.003 5) was the most important risk factor,followed by diabetes,anastomotic location.Conclusion More attention should be paid to postoperative anastomotic leakage risk factors.Satisfactory preoperative preparation,grasping the main points of rectal cancer surgery were the keys to the prevention of anastomotic leakage.

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Available abstract

Objective To investigate risk factors,prevention and treatment of postoperative anastomotic leakage in rectal cancer.Methods A total of 218 cases of low rectal anastomotic leakage were analyzed in risk factors.Conservative treatment and surgeries were used in patients with anastomotic leakage.Results Postoperative anastomotic leakage occurred in 19 patients(8.7%),conservative treatment in 17 cases and surgical treatment in 2 cases.There was a statistically significant difference in diabetes mellitus(P=0.019 6),serum albumin(P=0.003 1),anastomotic location(P=0.024 1).Logistic regression found that serum albumin level(OR=5.769,95% CI=1.751~23.712,P=0.003 5) was the most important risk factor,followed by diabetes,anastomotic location.Conclusion More attention should be paid to postoperative anastomotic leakage risk factors.Satisfactory preoperative preparation,grasping the main points of rectal cancer surgery were the keys to the prevention of anastomotic leakage.

Key concepts: Medicine, Anastomosis, Colorectal cancer, Diabetes mellitus, Logistic regression, Surgery, Conservative treatment, Internal medicine

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