Percutaneous Kyphoplasty for Non-osteoporotic Vertebral Compression Fracture

Objective:To evaluate the efficacy of percutaneous kyphoplasty in treating non-osteoporotic vertebral compression fractures.Methods:42 cases (11 male and 31 female) of vertebral compressive fractures (range 50 to 58,average 53.5 years old),were treated with percutaneous kyphoplasty under C armed imaging guiding. Preoperative bone mineral density examinations showed a reduction of bone mass,but failed to meet the diagnostic criteria for osteoporosis. The inflatable bone tamp was inserted into the fractured vertebral body transpedicularly in a minimally invasive way. The balloon was inflated,elevating the endplate and restoring vertebral body height and then confirmed by C armed imaging. The balloon was deflated and withdrawn,leaving a cavity within the vertebral body. The cavity was then filled with MIIGX3 artificial bone. The clinical effect was evaluated by observing the changes of visual analog scale (VAS),the use of pain-killer scale,the Cobb's angle and the height of vertebral bodies.Results:The back pain was marked relieved postoperatively. In the six weeks after the procedure,the patients were allowed to get off bed. VAS pain score improved from 8.2 0.65 preoperatively to 2.4 0.78 postoperatively and 2.6±0.67 at the last follow up(P0.01). The use of pain-killer scale were improved from1.6±0.48 preoperatively to 0.23±0.52 postoperatively and 0.24±0.55 at the last follow up(P0.01). The mean height of the anterior edge vertebral body was from 22.1 3.6mm preoperatively to 25.2 2.8mm postoperatively and 24.9 3.5mm at final follow-up (P0.01). The media vertebral bodies was increased from 21.8 2.9mm to 25.1 3.2mm,and at final follow-up 24.8 3.7mm (P0.01). The mean kyphosis was improved from 17.5°±5.5° to 13°±4.5°,and 13.5°±5.5° at final follow-up (P0.01).Conclusion:Percutaneous kyphoplasty for non-osteoporotic vertebral compression fracture could restore the height of fractured vertebra; relieve pain immediately,which should be a safe and effective minimal invasion spinal intervention.