Relationship between Binder point and prognosis of severe acute pancreatitis

Objective To investigate the relationship between Binder point and prognosis of severe acute pancreatitis (SAP). Methods The clinical data of 112 patients with SAP treated in our hospital in the past 19 years were retrospectively analyzed. Its prognosis was estimated based on the analysis of the relationship between death from SAP and Binder point and such complications as shock, ARDS, pancreatic brain disease and systemic infection etc. Results Of the 112 patients, 92 (82.1%) were cured and 20 died (17.8%). Seventy-three patients (65.2%) had complications. The rates of complications related to mortality of ARDS, shock, pancreatic brain disease and systemic infection were 6.3%, 7.1%, 5.3% and 3.5%, respectively. The patients were divided into above-7-point group and below-7-point group by the composite points based on the organic function failure or diabetic complications. The difference of mortality between the 2 groups was significant (P0.01). Conclusions Shock, ARDS, pancreatic brain disease and systemic infection are the main complications of SAP and major reasons for death. Binder point is correlated to these complications. The higher the point, the worse the prognosis.