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2010•Journal of Shenyang Medical CollegeRequires access

50 Cases with Hyperlipidemia Treated by Atorvastatin

Wei Zhang

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Abstract

Objective:To observe the effect of treatment of hyperlipidemia with atorvastatin.Methods:50 patients with total cholesterol(TC)≥6.5 mmol/L or triglyceride(TG)≥1.7 mmol/L or high-density lipoprotein cholesterol(HDL-C) ≤1.30 mmol/L were selected.Atorvastatin 10mg were given,day 1.At 8 weeks,the four lipids、blood、liver and kidney function,alanine aminotransferase(ALT),creatine kinase(CK) were measured.Results:Before and after treatment significant changes in blood lipids.total effective rate of improving blood TC,TG,LDL-C,HDL-C was 96.0%,72.0%,70.0% respectively.No significant adverse drug reactions were found.Conclusion:The effect of atorvastatin be treated for hyperlipidemia is significant,less side effects,it's meaningful for preventing cardiovascular daisease.

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What this paper is about

Objective:To observe the effect of treatment of hyperlipidemia with atorvastatin.Methods:50 patients with total cholesterol(TC)≥6.5 mmol/L or triglyceride(TG)≥1.7 mmol/L or high-density lipoprotein cholesterol(HDL-C) ≤1.30 mmol/L were selected.Atorvastatin 10mg were given,day 1.At 8 weeks,the four lipids、blood、liver and kidney function,alanine aminotransferase(ALT),creatine kinase(CK) were measured.Results:Before and after treatment significant changes in blood lipids.total effective rate of improving blood TC,TG,LDL-C,HDL-C was 96.0%,72.0%,70.0% respectively.No significant adverse drug reactions were found.Conclusion:The effect of atorvastatin be treated for hyperlipidemia is significant,less side effects,it's meaningful for preventing cardiovascular daisease.

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Available abstract

Objective:To observe the effect of treatment of hyperlipidemia with atorvastatin.Methods:50 patients with total cholesterol(TC)≥6.5 mmol/L or triglyceride(TG)≥1.7 mmol/L or high-density lipoprotein cholesterol(HDL-C) ≤1.30 mmol/L were selected.Atorvastatin 10mg were given,day 1.At 8 weeks,the four lipids、blood、liver and kidney function,alanine aminotransferase(ALT),creatine kinase(CK) were measured.Results:Before and after treatment significant changes in blood lipids.total effective rate of improving blood TC,TG,LDL-C,HDL-C was 96.0%,72.0%,70.0% respectively.No significant adverse drug reactions were found.Conclusion:The effect of atorvastatin be treated for hyperlipidemia is significant,less side effects,it's meaningful for preventing cardiovascular daisease.

Key concepts: Atorvastatin, Hyperlipidemia, Triglyceride, Medicine, Internal medicine, Creatine, Creatine kinase, Blood lipids

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