Progress on Porcine Circovirus Type 2 Associated Enteritis

Porcine circovirus-associated disease(PCVAD)has emerged as an economically important pig disease globally.Porcine circovirus type 2(PCV-2)-associated enteritis is one of PCVAD,and its clinical signs are diarrhea,growth retardation or weight loss in growing pigs.Large amounts of PCV-2specific antigens could be detected in intestines and lymohoid tissues,meanwhile characteristic microscopic lesions could be observed.It is reported that under experimental conditions,PCV-2could induce enteritis independently or together with other pathogens and oral challenge is an important infection route for PCV-2-associated enteritis.PCV-2is also a causative agent of enteric disorders in growing pigs,which needs more attention.In this article,the recent achievements in clinical signs,histopathological features,impact of multi-pathogen co-infection,diagnosis and control measures of PCV-2-associated enteritis were reviewed in order to serve as important references for researchers in this field.