2012•Zhongguo xiong-xin xueguan waike linchuang zazhiRequires access

Progress in Ischemic Postconditioning:A review

Limin Liu

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Abstract

Ischemia postconditioning is a new concept based on ischemic preconditioning.It has become a hot topic in protection of ischemic-reperfusion injury because of its effective protection,relative ease of application,and postconditioning.However,its precise mechanisms and most effective application methods are still unclear.This review covers recent progress in the understanding,developments(in remote postconditioning and pharmacological postconditioning), applications to the protection of heart,lung,liver,kidney,and brain,mechanisms and appropriate protocol of ischemic postconditioning.

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What this paper is about

Ischemia postconditioning is a new concept based on ischemic preconditioning.It has become a hot topic in protection of ischemic-reperfusion injury because of its effective protection,relative ease of application,and postconditioning.However,its precise mechanisms and most effective application methods are still unclear.This review covers recent progress in the understanding,developments(in remote postconditioning and pharmacological postconditioning), applications to the protection of heart,lung,liver,kidney,and brain,mechanisms and appropriate protocol of ischemic postconditioning.

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Available abstract

Ischemia postconditioning is a new concept based on ischemic preconditioning.It has become a hot topic in protection of ischemic-reperfusion injury because of its effective protection,relative ease of application,and postconditioning.However,its precise mechanisms and most effective application methods are still unclear.This review covers recent progress in the understanding,developments(in remote postconditioning and pharmacological postconditioning), applications to the protection of heart,lung,liver,kidney,and brain,mechanisms and appropriate protocol of ischemic postconditioning.

Key concepts: Medicine, Ischemic preconditioning, Ischemia, Cardiology

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