1999•Zhonghua yandibing zazhiRequires access
The observation on apoptosis from vitrectomy specimens of proliferative vitreoretinopathy
Xi Zhang
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Abstract
urpose To investigate apoptosis in vitrectomy specimens of
proliferative vitreoretinopathy. Methods Vitrectomy specimens from 60 cases of different
classes of proliferative vitreoretinopathy were studied by TdTmediated dUTP nick end
labelling(TUNEL)method. Results The characteristic change of apoptosis was observed in all
vitrectomy specimens.The amount of apoptotic nonpigmentary cell is gradually decreasing
along with the development of proliferative vitreoretinopathy,and apoptotic pigmentary cells are
observed. Conclusion There are different kinds of apoptosis cell in vitrectomy specimens of
proliferative vitreoretinopathy.It is suggested that apoptosis might be one of the important
mechanisms of regulating the degree in proliferative vitreoretinopathy.