Effect of genotype inspection on the diagnosis of the degree of hepatitis B virus infection

Objective To investigate the effect of genotype inspection on the diagnosis of the degree of hepatitis B virus(HBV)infection.Methods 120 cases of patients with HBV infection were enrolled from January 2014 to June 2014.The HBV DNA capacity,genotype and HBeAb were inspected.Results There were 82cases(68.33%)of HBV B genotype,30cases(25.00%)of HBV C genotype and 8cases(6.67%)of HBV B/C genotype,with significant difference between groups(P0.05).There was no significant correlation between HBV B genotype,HBV C genotype,HBV B/C genotype and HBV DNA capacity(P0.05).The HBeAb negative rate of patients infected by HBV B genotype was significantly higher than that of patients infected by HBV C genotype and HBV B/C genotype(P0.05).The HBeAb negative rate of patients infected by HBV B/C genotype was significantly higher than that of patients infected by HBV C genotype(P0.05).HBV B genotype was the main genotype of chronic hepatitis B,and HBV C genotype was the main genotype for primary hepatic carcinoma,with significant difference(P0.05).Conclusion In Heze area,HBV B genotype,HBV C genotype were the main genotypes for HBV infection.HBV genotype was correlated with infection degree and HBeAb negative rate,while not related with HBV DNA capacity.