Characteristics of migraine in children and adolescents and preventive treatment with flunarizin

Objective To analyze the epidemiological characteristics of migraine in children and adolescents and to observe the efficacy of the preventive treatment with flunarizine.Methods Based on the clinical symptoms,signs,medical history and auxiliary examination of migraine,the clinical characteristics,predisposing factors and classification of migraine in children and adolescents were analyzed.Those patients were administrated with flunarizine 10 mg orally once a day for eight weeks.Results Totally 200 migraine patients with clinical diagnosis were identified as migraine without aura for 56.0%,migraine with aura for 21.5%,periodic syndrome for 13%,retinal migraine for 5.5% and others for 4.0%.Among them tense learning(42.0%) and interpersonal discord(28.0%) were the most common predisposing factors.Seizure frequency and degree of migraine were decreased significantly after therapy with flunarizine.Conclusion The clinical characteristics,predisposing factors and classification may benefit to migraine identified.The flunarizine for migraine prophylactic treatment is effective and safe.