Study of Polymorphism on EPO Gene in Yak by PCR-SSCP

In this paper,the polymorphisms of hemopoietin(EPO)gene in Bazhou yak,Datong yak and Jiulong yak were investigated by PCR-SSCP and the results showed that the genetic diversity is rich among the three yak breeds.The genotypes are AA,AB and BB,in which AB genotype is the dominant genotype and allele A is the dominate allele.The χ2 compatibility test indicates that the gene frequencies of all of the three yak breeds are in Hardy-Weinberg equilibrium state.Simultaneously,this research also exhibits that the gene frequency of allele A rises up accompany with the increase of the altitude,while the BB allele frequency,colony heterozygosity and polymorphic information content rise down.This change possibly relates to the adaptive capacity to the oxygen-poor environments.