A study on the correlation between thrombocytosis and clinicopathological in patients with gastric cancer

Objective To study the prevalence of thrombocytosis in patients with gastric cancer and its correlation with clinicopathological features. Methods Platelet count (PLT) and hemoglobin concentrations (Hb) were analyzed retrospective in 366 patients with gastric cancer from 1986 to 1996. Thrombocytosis was defined as PLT at or 400×109/L and anemia was defined as Hb120g/L in men and110g/L in women. The survivals of gastric cancer was compared between normal PLT group and thrombocytosis group. Results Thrombocytosis was found in 24.6% patients, and anemia in 54.1% patients. PLT was negatively correlated with Hb. There was a positive correlation between tumor size, lymph node metastasis and serosal invasion and PLT. One-, 3- and 5-year survivals in patients with or without thrombocytosis were 50.4%,32.7%, 20.2% and 82.8%,69.3%, 40.1%, respectively. PLT was identified as an independent prognostic factor after lymph node metastasis and serosal invasion. ConclusionThrombocytosis is an independent prognostic indicator of survival in patients with gastric cancer undergoing gastrectomy.