Observation on therapeutic effect of Shengmai injection in the adjuvant treatment of patients with acute exacerbation of chronic pulmonary heart disease

Objective To observe the clinical therapeutic effect of Shengmai injection in the adjuvant treatment of patients with acute exacerbation of chronic pulmonary heart disease.Methods One hundred patients with acute exacerbation of chronic pulmonary heart disease were randomly divided into the Shengmai group (50 patients) and the control group (50 patients).The patients in two groups were treated with conventional western medicine treatment.On the basis of above treatment, the patients in the Shengmai group were given intravenous drip of Shengmai injection 60 ml added into 5% glucose injection,once daily.The treatment course was 14 days.Results Increasing of PaO_2 level and decreasing of PcO_2 level in the Shengmai group were more remarkable than those in the control group ( all P 0.01). Total effective rate in the Shengmai group ( 92% ) was higher than that in the control group (68%)( P 0.01).Except xerostomia which occured in 2 patients,there was no obvious adverse reaction in the Shengmai group.Conclusion Shengmai injection in the adjuvant treatment of patients with acute exacerbation of chronic pulmonary heart disease has obvious therapeutic effect and less adverse reaction.It is worthy of further application.