Evaluation of ~(99m)Tc-ECD SPECT in the early diagnosis of patients with acute ischemic cerebrovascular disease

Objective: To investigate the clinical value of 99mTc-ECD in the early diagnosis of patients with acute ischemic cerebrovascular disease. Method: Conducting SPECT and CT studies in the same patients less than 72 hours after the attack. Results: The positive rate of SPECT was 91.1%(4145). There was also a low regional cerebral blood flow in the affected area. The lesion was coincide with clinical symptoms. The positive rate of CT was 15.5%(745), the lesion appeared low density. After 6～24 hours and 24～72 hours from hypoxie-ischemic attack, 0, 7, 18 cases showed lesions on CT respectively. No case showed abnormality due to transient ischemic attack. The number of lesions showed on SPECT was more than that on CT. The difference was significant(χ2=13.5, P0.01). Conclusions: 99mTc-ECD SPECT can easily demonstrate a metabolic and functional lesions without structural abnormalities. It can detect cerebral blood flow change of intracerebral foci not detectable by traditional morphological imaging, 99mTc-ECD SPECT may give some reference in the early diagnosis and therapy of patients with acute ischemic cerebrovascular disease.