Study of Variation of Peripheral T Lymphocyte Subsets of Patients Infected HIV by Blood Transfusion

Objective To explore the variation of peripheral T lymphocyte subsets of patients infected human immunodeficiency virus(HIV) by blood transfusion.Methods Using the lymphocyte classification and streaming cell analysis on expression and absolute number testing of peripheral blood lymphocyte CD3+,CD4+,CD8+ of 20 cases of HIV carrier and 20 cases of acquired immune deficiency syndrome(AIDS).Results CD3+ lymphocyte number of AIDS group decreased more significantly than normal group(P0.05),CD4+T lymphocyte number of HIV and AIDS group decreased significantly(P0.01),CD8+ lymphocyte number increased significantly(P0.01),CD4+/CD8+ ratio inversion significantly.Conclusion The number of peripheral CD4+T lymphocyte decreased significantly after HIV infecting,the more significantly decline with progression.