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Serum Heart-type Fatty Acid Binding Protein—A New Biomarker of Tissue Injury

Meng Sh

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Abstract

Heart-type fatty acid binding protein(H-FABP)is a key fatty acid carrier protein.Human H-FABP is a kind of acid protein,with an isoelectric point of 5.1.At present,H-FABP is the most promising myocardial injury biomarker because it increases as early as zero to three hours from the onset of acute myocardial infarction.Its early release appears to be essentially dependent on ischemic myocardial injury.Compared with the established cardiac markers,H-FABP is a heart-specific and highly sensitive biomarker for the early diagnosis of acute coronary syndromes.In other tissue injury,H-FABP also has a high application value.

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What this paper is about

Heart-type fatty acid binding protein(H-FABP)is a key fatty acid carrier protein.Human H-FABP is a kind of acid protein,with an isoelectric point of 5.1.At present,H-FABP is the most promising myocardial injury biomarker because it increases as early as zero to three hours from the onset of acute myocardial infarction.Its early release appears to be essentially dependent on ischemic myocardial injury.Compared with the established cardiac markers,H-FABP is a heart-specific and highly sensitive biomarker for the early diagnosis of acute coronary syndromes.In other tissue injury,H-FABP also has a high application value.

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Available abstract

Heart-type fatty acid binding protein(H-FABP)is a key fatty acid carrier protein.Human H-FABP is a kind of acid protein,with an isoelectric point of 5.1.At present,H-FABP is the most promising myocardial injury biomarker because it increases as early as zero to three hours from the onset of acute myocardial infarction.Its early release appears to be essentially dependent on ischemic myocardial injury.Compared with the established cardiac markers,H-FABP is a heart-specific and highly sensitive biomarker for the early diagnosis of acute coronary syndromes.In other tissue injury,H-FABP also has a high application value.

Key concepts: Heart-type fatty acid binding protein, Fatty acid-binding protein, Biomarker, Isoelectric point, Myocardial infarction, Medicine, Cardiology, Internal medicine

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