2011Zhongguo shuxue zazhiRequires access

Comparison of the quality of fresh frozen plasma prepared by apheresis and that from whole blood

Zhao Shumin

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Abstract

Objective To compare the quality of fresh frozen plasma prepared by apheresis and that from whole blood.Methods Plasma prepared from apheresis(n=20) and donated whole blood(n=20) were stored in-30℃ refrigerator before testing.Coagulation factors(FⅧ,Fib) ,biochemical parameters(TP,LDH,K+,Na+,Cl-,FHb,pH) and Plt counts were determined.Results There were significant differences between the levels of FHb,K+,Na+,Cl-,Plt counts,but all could meet the current quality standards.In comparison to plasma prepared by centrifugation of donated whole blood,apheresis plasma showed a higher FⅧ.Conclusion There is no significant quality difference between apheresis fresh frozen plasma and the fresh frozen plasma prepared by centrifugation of donated whole blood.The levels of coagulation factors in the former are even higher than those of the latter.

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What this paper is about

Objective To compare the quality of fresh frozen plasma prepared by apheresis and that from whole blood.Methods Plasma prepared from apheresis(n=20) and donated whole blood(n=20) were stored in-30℃ refrigerator before testing.Coagulation factors(FⅧ,Fib) ,biochemical parameters(TP,LDH,K+,Na+,Cl-,FHb,pH) and Plt counts were determined.Results There were significant differences between the levels of FHb,K+,Na+,Cl-,Plt counts,but all could meet the current quality standards.In comparison to plasma prepared by centrifugation of donated whole blood,apheresis plasma showed a higher FⅧ.Conclusion There is no significant quality difference between apheresis fresh frozen plasma and the fresh frozen plasma prepared by centrifugation of donated whole blood.The levels of coagulation factors in the former are even higher than those of the latter.

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Available abstract

Objective To compare the quality of fresh frozen plasma prepared by apheresis and that from whole blood.Methods Plasma prepared from apheresis(n=20) and donated whole blood(n=20) were stored in-30℃ refrigerator before testing.Coagulation factors(FⅧ,Fib) ,biochemical parameters(TP,LDH,K+,Na+,Cl-,FHb,pH) and Plt counts were determined.Results There were significant differences between the levels of FHb,K+,Na+,Cl-,Plt counts,but all could meet the current quality standards.In comparison to plasma prepared by centrifugation of donated whole blood,apheresis plasma showed a higher FⅧ.Conclusion There is no significant quality difference between apheresis fresh frozen plasma and the fresh frozen plasma prepared by centrifugation of donated whole blood.The levels of coagulation factors in the former are even higher than those of the latter.

Key concepts: Apheresis, Fresh frozen plasma, Centrifugation, Whole blood, Chemistry, Cryopreservation, Blood preservation, Coagulation

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