Research about the receipient nerve regeneration induced by donor nerve's injury management in end-to-side neurorrhaphy

Objective Research about the receipient nerve regeneration induced by donor nerve's injury management in end-to-side neurorrhaphy.Methods Forty sides of hind limbs of twenty SD male rats were randomly divided into 2 groups:In group A,the peroneal was transected and tibial nerve was resected half horizontly.Distal end of transected peroneal nerve on the left side was sutured to windowed tibial nerve in an end-to-side fashion with 45 angle.In group B,tibial nerve was not transected and the remaining procedures were identical with the above.2 months after operation,histological examination,nerve conduction velocity examination,electro-physiology examination,tibialis anterior muscle wet measurement,electron microscopic examination were performed.Results Wet muscle measurement made no significance (P0.05).The difference of peroneal nerve conduct velocity (P0.05),the number of regenerated peroneal nerve got significant difference (P0.01).The tibial nerve's conduct velocity in group A was superior to group B.Conclusion The horizontal resection to the donor nerve,which inserts harmful effect on the donor nerve,is necceseary for the nerve regeneration.Further research will be made to the nerve regeneration on the condition of donor nerve's horizontal resection