The role of the homeobox gene in gastrointestinal development and gastrointestinal tumorigenesis
Zhu Zheng
Abstract
Zhu Zheng
Abstract
Homeobox gene,with two subgroups-HOX gene and Para-HOX gene,plays a key role in embryonic development process as a conserved gene family;And for the past few years,more and more attention were payed on the relationship between the homeobox gene and tumor.This paper focus on the role of the homeobox gene in gastrointestinal development and tumorigenesis.
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Homeobox gene,with two subgroups-HOX gene and Para-HOX gene,plays a key role in embryonic development process as a conserved gene family;And for the past few years,more and more attention were payed on the relationship between the homeobox gene and tumor.This paper focus on the role of the homeobox gene in gastrointestinal development and tumorigenesis.
Key concepts: Homeobox, Homeobox A1, HNF1B, Homeobox protein Nkx-2.5, Hox gene, CDX2, Carcinogenesis, DLX5