2006International Journal of Digestive DiseaseRequires access

The role of the homeobox gene in gastrointestinal development and gastrointestinal tumorigenesis

Zhu Zheng

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Abstract

Homeobox gene,with two subgroups-HOX gene and Para-HOX gene,plays a key role in embryonic development process as a conserved gene family;And for the past few years,more and more attention were payed on the relationship between the homeobox gene and tumor.This paper focus on the role of the homeobox gene in gastrointestinal development and tumorigenesis.

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What this paper is about

Homeobox gene,with two subgroups-HOX gene and Para-HOX gene,plays a key role in embryonic development process as a conserved gene family;And for the past few years,more and more attention were payed on the relationship between the homeobox gene and tumor.This paper focus on the role of the homeobox gene in gastrointestinal development and tumorigenesis.

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Available abstract

Homeobox gene,with two subgroups-HOX gene and Para-HOX gene,plays a key role in embryonic development process as a conserved gene family;And for the past few years,more and more attention were payed on the relationship between the homeobox gene and tumor.This paper focus on the role of the homeobox gene in gastrointestinal development and tumorigenesis.

Key concepts: Homeobox, Homeobox A1, HNF1B, Homeobox protein Nkx-2.5, Hox gene, CDX2, Carcinogenesis, DLX5

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