Clinical observation of the effect of two different methods on induction of labor of gravidas with full-term pregnancy after artificial rupture of membranes.

Objective To investigate the safety and efficacy of intravaginal misoprostol for induction of labor of gravidas with full-term pregnancy after artificial rupture of membranes.Methods One hundred unipara(age 23～35 years) with full-term singleton pregnancy,cephalic presentation and cervical Bishop score7,were randomly assigned to receive intravaginal misoprostol(n = 60) or intravenous oxytocin(n = 40).Rusults There were no significant differences between two groups in the efficacy of induction of labor(P0.05),the duration of induction of labor in the misoprostol group was significantly shorter than that in the oxytocin group(P0.01).Conclusion Intravaginal misoprostol may be an effective and safe method for induction of labor after artificial rupture of membranes,misoprostol can accelerate cervical ripeness and uterus systole.