Contents of Anti-cancer Active Components in Plant of Taxus yunnanensis

Taxus yunnanensis is the major species for producing anti-cancer medicine taxol in China. According to the determination data of taxol,10-Deacety-BaccatinⅢ and BaccatinⅢ on samples of Taxus yunnanensis plants,and the determination data of Taxus yunnanensis was compared with other species of Taxus.The analysis and comparison results showed that Taxus yunnanensis is a species with high content of those three components.The taxol content of bark of Taxus yunnanensis trees from natural forests is around 0.02 %,with the highest percentage of 0.030 4 %. The average content in small branch and leaf is 0.010 2 % and with the highest percentage of 0.021 7 %.The content of Baccatin is high up to 0.080 8 % and 0.084 5 % in bark and small branch leaf respectively. Furthermore,the content of active components in plants from plantation does not decreased sharply.The taxol content in root of Taxus yunnanensis plant from plantation is 0.042 1 % ～ 0.046 0 %,the content of Baccatin is high up to 0.103 %.The content of different active components in Taxus yunnanensis plant all attained the high level of world famous raw material tree species,Taxus madia and Taxus bauata.There are significant different between the active component contents between different samples, the differences varies from several times up to 17 times. Following three reasons might cause this kind of difference,1)Genetic difference;2)Difference in ecological environment;3)Difference in managing, storing, analyzing and determining.It is promising to heighten the contents of active components by improving from these three aspects.