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[Smoking impairs endothelial function in ED patients].

Fengjuan Yao, Yanping Huang, Hong Lin, Donghong Liu, Rui Fan, Yanqiu Liu, Kun Lü, Chunhua Deng, Xiangzhou Sun

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Abstract

OBJECTIVE: To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease. METHODS: This study included 69 ED patients (21 smokers and 48 non-smokers) and 16 age-matched normal healthy controls. All underwent measurement of brachial artery flow-mediated vasodilation (FMD) and examinations of blood pressure, cholesterol, triglycerides and glucose. RESULTS: Brachial artery FMD was remarkably decreased in the ED patients, even more significantly in the smokers ([6.0 +/- 0.8]%) than in the non-smokers ([9.7 +/- 2.5]%) (P < 0.05), as compared with that in the normal healthy controls ([14.0 +/- 2. 5]%, P < 0.05). CONCLUSION: Endothelial function is impaired in ED patients, and is further damaged by smoking.

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What this paper is about

OBJECTIVE: To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease. METHODS: This study included 69 ED patients (21 smokers and 48 non-smokers) and 16 age-matched normal healthy controls. All underwent measurement of brachial artery flow-mediated vasodilation (FMD) and examinations of blood pressure, cholesterol, triglycerides and glucose. RESULTS: Brachial artery FMD was remarkably decreased in the ED patients, even more significantly in the smokers ([6.0 +/- 0.8]%) than in the non-smokers ([9.7 +/- 2.5]%) (P < 0.05), as compared with that in the normal healthy controls ([14.0 +/- 2. 5]%, P < 0.05). CONCLUSION: Endothelial function is impaired in ED patients, and is further damaged by smoking.

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Available abstract

OBJECTIVE: To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease. METHODS: This study included 69 ED patients (21 smokers and 48 non-smokers) and 16 age-matched normal healthy controls. All underwent measurement of brachial artery flow-mediated vasodilation (FMD) and examinations of blood pressure, cholesterol, triglycerides and glucose. RESULTS: Brachial artery FMD was remarkably decreased in the ED patients, even more significantly in the smokers ([6.0 +/- 0.8]%) than in the non-smokers ([9.7 +/- 2.5]%) (P < 0.05), as compared with that in the normal healthy controls ([14.0 +/- 2. 5]%, P < 0.05). CONCLUSION: Endothelial function is impaired in ED patients, and is further damaged by smoking.

Key concepts: Brachial artery, Medicine, Vasodilation, Endothelial dysfunction, Internal medicine, Blood pressure, Cardiology, Endothelium

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