Quality Standard of Zhikuoning Mixture
Cao Shihong
Abstract
Cao Shihong
Abstract
OBJECTIVE:To establish the quality standard of Zhikuoning mixture.METHODS:Scutellaria baicalensis,Morus alba,Citrus aurantinm,Salvia miltiorrhiza in the preparation were identified by TLC,and the content of baicalin in Zhikuoning mixture was determined by HPLC.RESULTS:The TLC spots were clear and well-isolated yet without interference from negative control.The linear range of Baicalin was 15.81~252.96 μg·mL-1(r=0.999 9)and its average recovery was 101.8%(RSD=1.80%,n=9).CONCLUSION:The established quality standard can be used for the quality control of Zhikuoning mixture.
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OBJECTIVE:To establish the quality standard of Zhikuoning mixture.METHODS:Scutellaria baicalensis,Morus alba,Citrus aurantinm,Salvia miltiorrhiza in the preparation were identified by TLC,and the content of baicalin in Zhikuoning mixture was determined by HPLC.RESULTS:The TLC spots were clear and well-isolated yet without interference from negative control.The linear range of Baicalin was 15.81~252.96 μg·mL-1(r=0.999 9)and its average recovery was 101.8%(RSD=1.80%,n=9).CONCLUSION:The established quality standard can be used for the quality control of Zhikuoning mixture.
Key concepts: Baicalin, Quality standard, Chromatography, Scutellaria baicalensis, Salvia miltiorrhiza, Chemistry, Negative control, Traditional medicine