2006Journal of Practical Medical TechniquesRequires access

The Function of Prealbumin in Evaluating Alcoholic Liver Disease(ALD)

Qin Li

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Abstract

Objective In order to confirm clinical pathologic attribution of ALD,and to identify with other hepatopathy.We studied the function of prealbumin in evaluation of alcoholic fatty liver,alcoholic hepatitis,alcoholic cirrhosis.Methods In accordance with clinical diagnosis criteria of ALD(discussion manuscript)formulated by the Branch of Adiposis Hepatica and Alcoholic Liver Disease Chinese Society of Hepatology Chinese Medical Association,we selected sixty-five patient.Then we measured prealbumin(PA)in their serum.Results In chronic persistant hepatitis,alcoholic fatty liver,alcoholic hepatitis and alcoholic cirrhosis,the content of ALT,AST and GGT was not significant different.In Alcoholic fatty liver and alcoholic hepatitis,the content of PA was not decreased significantly.However,PA was decreased significantly in alcoholic cirrhosis and chronic active hepatitis.Conclusion We could check PA when the content of ALT,AST and GGT was all increased,but we could not judge which of them was increased in patient drinking for along time.Patient whose PA was normal could suffer from alcoholic fatty liver.They can becured by stoping drinking.Patient whose PA was decreased significantly could suffer from hepatic cirrhosis and chronic persistant hepatitis.In order to cure they shoud be checked other item.

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Objective In order to confirm clinical pathologic attribution of ALD,and to identify with other hepatopathy.We studied the function of prealbumin in evaluation of alcoholic fatty liver,alcoholic hepatitis,alcoholic cirrhosis.Methods In accordance with clinical diagnosis criteria of ALD(discussion manuscript)formulated by the Branch of Adiposis Hepatica and Alcoholic Liver Disease Chinese Society of Hepatology Chinese Medical Association,we selected sixty-five patient.Then we measured prealbumin(PA)in their serum.Results In chronic persistant hepatitis,alcoholic fatty liver,alcoholic hepatitis and alcoholic cirrhosis,the content of ALT,AST and GGT was not significant different.In Alcoholic fatty liver and alcoholic hepatitis,the content of PA was not decreased significantly.However,PA was decreased significantly in alcoholic cirrhosis and chronic active hepatitis.Conclusion We could check PA when the content of ALT,AST and GGT was all increased,but we could not judge which of them was increased in patient drinking for along time.Patient whose PA was normal could suffer from alcoholic fatty liver.They can becured by stoping drinking.Patient whose PA was decreased significantly could suffer from hepatic cirrhosis and chronic persistant hepatitis.In order to cure they shoud be checked other item.

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Available abstract

Objective In order to confirm clinical pathologic attribution of ALD,and to identify with other hepatopathy.We studied the function of prealbumin in evaluation of alcoholic fatty liver,alcoholic hepatitis,alcoholic cirrhosis.Methods In accordance with clinical diagnosis criteria of ALD(discussion manuscript)formulated by the Branch of Adiposis Hepatica and Alcoholic Liver Disease Chinese Society of Hepatology Chinese Medical Association,we selected sixty-five patient.Then we measured prealbumin(PA)in their serum.Results In chronic persistant hepatitis,alcoholic fatty liver,alcoholic hepatitis and alcoholic cirrhosis,the content of ALT,AST and GGT was not significant different.In Alcoholic fatty liver and alcoholic hepatitis,the content of PA was not decreased significantly.However,PA was decreased significantly in alcoholic cirrhosis and chronic active hepatitis.Conclusion We could check PA when the content of ALT,AST and GGT was all increased,but we could not judge which of them was increased in patient drinking for along time.Patient whose PA was normal could suffer from alcoholic fatty liver.They can becured by stoping drinking.Patient whose PA was decreased significantly could suffer from hepatic cirrhosis and chronic persistant hepatitis.In order to cure they shoud be checked other item.

Key concepts: Medicine, Alcoholic liver disease, Alcoholic hepatitis, Fatty liver, Internal medicine, Gastroenterology, Cirrhosis, Alcoholic fatty liver

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