ScholarLens Back to search
2004•Medical Laboratory SciencesRequires access

Application of ROC curve in the evaluation of laboratory tests for the diagnosis of hyperthyroidism

Liu Chengy

Open publisher page 0 citations

Abstract

Objective To evaluate the accuracy of six laboratory tests for the diagnosis of hyperthyroidism. Methods The levels of TT3,TT4,FT3,FT4,rT3 and s-TSH in 150 patients with hyperthyroidism and 100 normal persons were measured by RIA and IRMA. Receiver operating characteristic (ROC) curve was drawn, and the area under the curve was calculated. Results The area under ROC curve of S s-TSH ,S FT3 ,S TT3 ,S FT4 ,S rT3 and S TT4 was 0.957,0.952,0.933,0.905,0.899 and 0.874 respectively. Conclusions The accuracy of s-TSH and FT3 is the best in diagnosis of hyperthyroidism according to the ROC curve evaluation.

About this research paper

What this paper is about

Objective To evaluate the accuracy of six laboratory tests for the diagnosis of hyperthyroidism. Methods The levels of TT3,TT4,FT3,FT4,rT3 and s-TSH in 150 patients with hyperthyroidism and 100 normal persons were measured by RIA and IRMA. Receiver operating characteristic (ROC) curve was drawn, and the area under the curve was calculated. Results The area under ROC curve of S s-TSH ,S FT3 ,S TT3 ,S FT4 ,S rT3 and S TT4 was 0.957,0.952,0.933,0.905,0.899 and 0.874 respectively. Conclusions The accuracy of s-TSH and FT3 is the best in diagnosis of hyperthyroidism according to the ROC curve evaluation.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To evaluate the accuracy of six laboratory tests for the diagnosis of hyperthyroidism. Methods The levels of TT3,TT4,FT3,FT4,rT3 and s-TSH in 150 patients with hyperthyroidism and 100 normal persons were measured by RIA and IRMA. Receiver operating characteristic (ROC) curve was drawn, and the area under the curve was calculated. Results The area under ROC curve of S s-TSH ,S FT3 ,S TT3 ,S FT4 ,S rT3 and S TT4 was 0.957,0.952,0.933,0.905,0.899 and 0.874 respectively. Conclusions The accuracy of s-TSH and FT3 is the best in diagnosis of hyperthyroidism according to the ROC curve evaluation.

Key concepts: Receiver operating characteristic, Area under the curve, Medicine, Area under curve, Diagnostic accuracy, Internal medicine, Gastroenterology, Pharmacokinetics

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Application of ROC curve in the evaluation of laboratory tests for the diagnosis of hyperthyroidism — Research Paper | ScholarLens