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A new phenolic glycoside from fruits of Citrus aurantium

Wen‐Cai Ye

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Abstract

Objective To study the bioactive constituents of the immature fruits of Citrus aurantium. Methods Silica gel and Sephadex LH-20 were used to isolate the constituents of this plant. The spectroscopic methods were applied for their structural elucidation. Results Four compounds were isolated from the ethanol extract of the immature fruits of C. aurantium. These compounds were elucidated as 3, 5-dihydroxyphenyl 1-O-(6′-O-trans-feruloyl)-β-D-glucopyranoside (Ⅰ), hesperetin (Ⅱ), 4′, 5, 7, 8-tetra- methoxyflavone (Ⅲ), and limonin (Ⅳ). Conclusion Compound Ⅰ is a new phenolic glycoside.

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What this paper is about

Objective To study the bioactive constituents of the immature fruits of Citrus aurantium. Methods Silica gel and Sephadex LH-20 were used to isolate the constituents of this plant. The spectroscopic methods were applied for their structural elucidation. Results Four compounds were isolated from the ethanol extract of the immature fruits of C. aurantium. These compounds were elucidated as 3, 5-dihydroxyphenyl 1-O-(6′-O-trans-feruloyl)-β-D-glucopyranoside (Ⅰ), hesperetin (Ⅱ), 4′, 5, 7, 8-tetra- methoxyflavone (Ⅲ), and limonin (Ⅳ). Conclusion Compound Ⅰ is a new phenolic glycoside.

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Available abstract

Objective To study the bioactive constituents of the immature fruits of Citrus aurantium. Methods Silica gel and Sephadex LH-20 were used to isolate the constituents of this plant. The spectroscopic methods were applied for their structural elucidation. Results Four compounds were isolated from the ethanol extract of the immature fruits of C. aurantium. These compounds were elucidated as 3, 5-dihydroxyphenyl 1-O-(6′-O-trans-feruloyl)-β-D-glucopyranoside (Ⅰ), hesperetin (Ⅱ), 4′, 5, 7, 8-tetra- methoxyflavone (Ⅲ), and limonin (Ⅳ). Conclusion Compound Ⅰ is a new phenolic glycoside.

Key concepts: Limonin, Chemistry, Glycoside, Sephadex, Hesperetin, Mangiferin, Pomace, Traditional medicine

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