ScholarLens Back to search
2010•Journal of clinical and experimental medicineRequires access

Clinical control study on sertraline combined with cognitive therapy in treatment of depression

Quan Quan-shen

Open publisher page 0 citations

Abstract

Objective To explore the efficacy and safety of sertraline combined with cognitive therapy in treatment of patients with depression.Methods Eighty outpatients were randomly assigned to receiving cognitive therapy plus sertraline(n=40)and only receiving sertraline(n=40)for 6 weeks.The efficacy was assessed with Hanmilton depressive scale(HAMD)and self-rating depressive scale(SDS)before and after treatment in 2nd,4th and 6th weekend.Results At the end of 4th and 6th weekend,SDS and HAMD scores of patients in cognitive therapy group decreased significantly than those before treatment,and their SDS and HAMD scores were significantly lowered than those of sertraline group.Conclusion It is suggested that sertraline combined with cognitive therapy may be a better measure for treatment of depression.

About this research paper

What this paper is about

Objective To explore the efficacy and safety of sertraline combined with cognitive therapy in treatment of patients with depression.Methods Eighty outpatients were randomly assigned to receiving cognitive therapy plus sertraline(n=40)and only receiving sertraline(n=40)for 6 weeks.The efficacy was assessed with Hanmilton depressive scale(HAMD)and self-rating depressive scale(SDS)before and after treatment in 2nd,4th and 6th weekend.Results At the end of 4th and 6th weekend,SDS and HAMD scores of patients in cognitive therapy group decreased significantly than those before treatment,and their SDS and HAMD scores were significantly lowered than those of sertraline group.Conclusion It is suggested that sertraline combined with cognitive therapy may be a better measure for treatment of depression.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the efficacy and safety of sertraline combined with cognitive therapy in treatment of patients with depression.Methods Eighty outpatients were randomly assigned to receiving cognitive therapy plus sertraline(n=40)and only receiving sertraline(n=40)for 6 weeks.The efficacy was assessed with Hanmilton depressive scale(HAMD)and self-rating depressive scale(SDS)before and after treatment in 2nd,4th and 6th weekend.Results At the end of 4th and 6th weekend,SDS and HAMD scores of patients in cognitive therapy group decreased significantly than those before treatment,and their SDS and HAMD scores were significantly lowered than those of sertraline group.Conclusion It is suggested that sertraline combined with cognitive therapy may be a better measure for treatment of depression.

Key concepts: Sertraline, Hamd, Medicine, Depression (economics), Rating scale, Internal medicine, Hamilton depression scale, Cognition

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical control study on sertraline combined with cognitive therapy in treatment of depression — Research Paper | ScholarLens