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Therapeutic effect of trans-arterial chemo-embolization in combination with radio-frequency ablation for the treatment of middle or advanced stage hepatocellular carcinoma

Dai Xiang-dang

Open publisher page 2 citations

Abstract

Objective:To evaluate the clinical value of trans-arterial chemoembolization(TACE)in combination with radio-frequency ablation(RFA)for the treatment of middle or advanced stage hepatocellular carcanoma(HCC).Methods:112 cases with pathology,AFP or imaging diagnosed middle or advanced stage HCC were divided into 2 groups according to their treatment.54 patients were enrolled into TACE group and 58 patients into the TACE+RFA group.Results:The effective rate was 44% for the TACE group and 68% for the TACE+RFA group,significant statistical difference was existed(P0.01).The 1,2 and 3 year's survival rate of TACE group was 85%,64% and 23% respectively,with a median survival of 1.725 years.The 1,2 and 3 year's survival rate of TACE+RFA group was 93%,88% and 79% respectively and the median survival was 2.296 years.The survival of TACE+RFA group was significantly higher than that of TACE group(P0.05).Conclusion:TACE+RFA can significantly increase the survival rate for patients with middle or advanced stage hepatocellular carcinoma.

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What this paper is about

Objective:To evaluate the clinical value of trans-arterial chemoembolization(TACE)in combination with radio-frequency ablation(RFA)for the treatment of middle or advanced stage hepatocellular carcanoma(HCC).Methods:112 cases with pathology,AFP or imaging diagnosed middle or advanced stage HCC were divided into 2 groups according to their treatment.54 patients were enrolled into TACE group and 58 patients into the TACE+RFA group.Results:The effective rate was 44% for the TACE group and 68% for the TACE+RFA group,significant statistical difference was existed(P0.01).The 1,2 and 3 year's survival rate of TACE group was 85%,64% and 23% respectively,with a median survival of 1.725 years.The 1,2 and 3 year's survival rate of TACE+RFA group was 93%,88% and 79% respectively and the median survival was 2.296 years.The survival of TACE+RFA group was significantly higher than that of TACE group(P0.05).Conclusion:TACE+RFA can significantly increase the survival rate for patients with middle or advanced stage hepatocellular carcinoma.

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Available abstract

Objective:To evaluate the clinical value of trans-arterial chemoembolization(TACE)in combination with radio-frequency ablation(RFA)for the treatment of middle or advanced stage hepatocellular carcanoma(HCC).Methods:112 cases with pathology,AFP or imaging diagnosed middle or advanced stage HCC were divided into 2 groups according to their treatment.54 patients were enrolled into TACE group and 58 patients into the TACE+RFA group.Results:The effective rate was 44% for the TACE group and 68% for the TACE+RFA group,significant statistical difference was existed(P0.01).The 1,2 and 3 year's survival rate of TACE group was 85%,64% and 23% respectively,with a median survival of 1.725 years.The 1,2 and 3 year's survival rate of TACE+RFA group was 93%,88% and 79% respectively and the median survival was 2.296 years.The survival of TACE+RFA group was significantly higher than that of TACE group(P0.05).Conclusion:TACE+RFA can significantly increase the survival rate for patients with middle or advanced stage hepatocellular carcinoma.

Key concepts: Medicine, Hepatocellular carcinoma, Stage (stratigraphy), Radiofrequency ablation, Survival rate, Transcatheter arterial chemoembolization, Ablation, Overall survival

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