Risk Factors and Prevention of Hematoma Enlargement after Spontaneous Intracerebral Hemorrhage

Objective To explore the risk factors and preventive measures of the hematoma enlargement after spontaneous intracerebral hemorrhage(ICH).Methods The patients with spontaneous intracerebral hemorrhage were divided into hematoma enlargement group(31 cases) and control group(101 cases).The congenital factors,past medical history,behavioral factors,clinical factors and other relevant factors were compared between the two groups.Results As compared to the control group,the hematoma enlargement group had higher rates in male patients,especially those with history of liver diseases,aspirin taking and heavy drinking;the course was shorter,the systolic blood pressure was higher;more cases were with the thalamic hemorrhage,irregular hemorrhage shapes,vomiting and restless,and needed mannitol treatment in 24 hours.Conclusion The younger male ICH patients especially with the history of liver diseases,aspirin taking and heavy drinking should have a high rate of hematoma enlargement.The risk factors include the increased systolic blood pressure in the early stage of ICH,the hemorrhage position in thalamus,irregular hemorrhage shapes,vomiting and restless after onset of ICH and early need of mannitol treatment.