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Radiotherapy for Esophageal Carcinoma After Radical Resection

Jiaxin Chen

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Abstract

objective To evaluate radiotherapy for esophageal carcinoma after radical resection. Method Between 1985 and 1992, 24 patients with esophageal carcinoma were treated by radiotherapy after radical resection (A group ) , Basing on the same period and clinical stages of A group ,24 patients without radiotherapy served as control(B group) randomly The radiation dose was DT50~60Gy/5~7w The survival rates were analyzed with Kaplan-Keier method and Log-rank test Result The 1-,3-and 5-year survival rates of A group were 95 8% (23/24),78 3%(18/23),54 5%(12/22),respectively, of B group were 87 5%(21/24),66 7%(16/24),34 8%(8/23), respectively( P0 05) The metastases rates of A group was12 5%(3/24),of B group was 16 7%(4/24)(P0 05) The local regional recurrence rates of A group was25 0%(6/24),of B group was 58 3%(14/24),the latter was significantly higher than the former (P=0 02) Conclusion radiotherapy for esophageal carcinoma after radical resection can reduce local regional recurrence rate

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objective To evaluate radiotherapy for esophageal carcinoma after radical resection. Method Between 1985 and 1992, 24 patients with esophageal carcinoma were treated by radiotherapy after radical resection (A group ) , Basing on the same period and clinical stages of A group ,24 patients without radiotherapy served as control(B group) randomly The radiation dose was DT50~60Gy/5~7w The survival rates were analyzed with Kaplan-Keier method and Log-rank test Result The 1-,3-and 5-year survival rates of A group were 95 8% (23/24),78 3%(18/23),54 5%(12/22),respectively, of B group were 87 5%(21/24),66 7%(16/24),34 8%(8/23), respectively( P0 05) The metastases rates of A group was12 5%(3/24),of B group was 16 7%(4/24)(P0 05) The local regional recurrence rates of A group was25 0%(6/24),of B group was 58 3%(14/24),the latter was significantly higher than the former (P=0 02) Conclusion radiotherapy for esophageal carcinoma after radical resection can reduce local regional recurrence rate

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Available abstract

objective To evaluate radiotherapy for esophageal carcinoma after radical resection. Method Between 1985 and 1992, 24 patients with esophageal carcinoma were treated by radiotherapy after radical resection (A group ) , Basing on the same period and clinical stages of A group ,24 patients without radiotherapy served as control(B group) randomly The radiation dose was DT50~60Gy/5~7w The survival rates were analyzed with Kaplan-Keier method and Log-rank test Result The 1-,3-and 5-year survival rates of A group were 95 8% (23/24),78 3%(18/23),54 5%(12/22),respectively, of B group were 87 5%(21/24),66 7%(16/24),34 8%(8/23), respectively( P0 05) The metastases rates of A group was12 5%(3/24),of B group was 16 7%(4/24)(P0 05) The local regional recurrence rates of A group was25 0%(6/24),of B group was 58 3%(14/24),the latter was significantly higher than the former (P=0 02) Conclusion radiotherapy for esophageal carcinoma after radical resection can reduce local regional recurrence rate

Key concepts: Medicine, Radiation therapy, Carcinoma, Group B, Survival rate, Surgery, Resection, Group A

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