Analysis of Cell Morphology and serum immunoglobulin in 208 Patients with Multiple Myeloma

Objective To detect the significance of bone marrow cell morphology and serum immunoglobulin in 208 patients with multiple myeloma(MM) through retrospevtive research,And based on that to evaluate their uses in diagnossis of MM.Methods The clinical features of 208 patients with MM were retrospectively analyzed and further analyzed myeloma cell ratio and morphology type in bone marrow;In mean time datas of serum immunoglobulin are analyzed.Results In 208 patients:Myeloma cell percentage10% in bone marrow slide were 204/98.1%,myeloma cell percentage between 6%-10% are 3/1.4%,no raise1/0.5%;clinical features with MM:osteoclasia(168/80.1%),anemia(163/79.5%),osteodynia(146/70.1%),renal functional abnormality(102/49%),bleeding(8/3.8%);serum immunoglobulin:IgG 28/61%,IgA 47/22.7%,light chain type 28/13.7%,no secretion 5/2.8%.Conclusion Morphology of bone marrow cell is an important method in MM diagnosis,while the clinical features,serum immunoglobulin also should be recommended.