Huang Suo-yi, Tian Hua
Abstract
2-Fluoro-4-iodo-anisole was synthesized from o-amino- anisole by Schiemann reaction.Resulting in o- fluoro-anisole,then nitating and reduction at 4-position of aromatic ring followed by Sandmeyer reaction of iodo.It is the intermediate of L-3-F-tyrosine.
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2-Fluoro-4-iodo-anisole was synthesized from o-amino- anisole by Schiemann reaction.Resulting in o- fluoro-anisole,then nitating and reduction at 4-position of aromatic ring followed by Sandmeyer reaction of iodo.It is the intermediate of L-3-F-tyrosine.
Key concepts: Anisole, Chemistry, Ring (chemistry), Medicinal chemistry, Organic chemistry, Catalysis