The study on the clinical significance of the serum transferrin receptor in the diagnosis and the degree of the iron deficiency anemia

Objective: To observe the clinical significance of the serum transferrin receptor (sTfR) in the diagnosis and the degree of the iron deficiency anemia (IDA) in children. Methods: 20 normal controls and 50 IDA patients of 6 months-12 years were made the determination of sTfR , Hb and serum ferritin (SF) et al, all the children were divided into three groups; normal controls (C) , mild IDA group (IDA1) and moderate to severe IDA group (IDA2), and made statistical analysis among the three groups' mean level of the sTfR. Results: The mean level of sTfR in the IDA2 and the IDAl were significantly higher than these the normal controls, and the mean level of the IDA2 was also significantly higher than the IDA1, so the mean level of the sTfR in the three groups were different significantly from each others (P0. 01) . Conclusion: The sTfR has great significance in the diagnosis and the degree of IDA in children.