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2014•Zhongguo weishengtaixue zazhiRequires access

Advances and clinical significance of serum tumor markers in lung cancer

Yangwu Ren

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Abstract

Lung cancer shows a tendency of higher incidence and higher mortality in recent years,but the overall 5-year survival rate is less than 10%-15%. Serum tumor markers have important significance in early screening, diagnosis,efficacy evaluation,recurrence and prognosis of lung cancer. In this paper,5 most important lung cancer serum tumor markers were reviewed,including carcinoembryonic antigen( CEA),neuron-specific enolase( NSE),cytokeratin fragment antigen 21-1( CYFRA21-1),squamous cell carcinoma related antigen( SCC-Ag) and lactate dehydrogenase( LDH).

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Lung cancer shows a tendency of higher incidence and higher mortality in recent years,but the overall 5-year survival rate is less than 10%-15%. Serum tumor markers have important significance in early screening, diagnosis,efficacy evaluation,recurrence and prognosis of lung cancer. In this paper,5 most important lung cancer serum tumor markers were reviewed,including carcinoembryonic antigen( CEA),neuron-specific enolase( NSE),cytokeratin fragment antigen 21-1( CYFRA21-1),squamous cell carcinoma related antigen( SCC-Ag) and lactate dehydrogenase( LDH).

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Available abstract

Lung cancer shows a tendency of higher incidence and higher mortality in recent years,but the overall 5-year survival rate is less than 10%-15%. Serum tumor markers have important significance in early screening, diagnosis,efficacy evaluation,recurrence and prognosis of lung cancer. In this paper,5 most important lung cancer serum tumor markers were reviewed,including carcinoembryonic antigen( CEA),neuron-specific enolase( NSE),cytokeratin fragment antigen 21-1( CYFRA21-1),squamous cell carcinoma related antigen( SCC-Ag) and lactate dehydrogenase( LDH).

Key concepts: Enolase, Carcinoembryonic antigen, Lung cancer, Tumor marker, Clinical significance, Cytokeratin, Lactate dehydrogenase, Medicine

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