ScholarLens Back to search
2011•Chinese Journal of General PracticeRequires access

Value of Detecting Serum Cystatin C in Diagnosis of Kidney Disease

Yuanming Zhao

Open publisher page 0 citations

Abstract

Objective To discuss the value of serum Cystatin C as a sensitive mark in the clinical diagnosis of renal dysfunction and injury.Methods The serum levels of Cys C,Creatinin(Scr) and blood urea nitrogen(BUN) of 63 patients were detected by the immune turbidimetry and enzyme methods.The creantinine clearance(Ccr) was calculated by using Cockcroft-Gault formula.Results The mean levels of Cys C,Scr and BUN increased with the decrease of Ccr(P0.05).The ratio of patients with abnormal Cys C and Scr were 56% and 22% in groupⅠ(n=18),77% and 31% in group Ⅱ(n=26) and 100% and 100% in group Ⅲ(n=19),respectively.Conclusion Serum Cys C is a sensitive mark of renal injury.It can be detected easily and effectively used to evaluate the glomerular filtration function as compared with the endogenous creatinine clearane(Ccr) method.

About this research paper

What this paper is about

Objective To discuss the value of serum Cystatin C as a sensitive mark in the clinical diagnosis of renal dysfunction and injury.Methods The serum levels of Cys C,Creatinin(Scr) and blood urea nitrogen(BUN) of 63 patients were detected by the immune turbidimetry and enzyme methods.The creantinine clearance(Ccr) was calculated by using Cockcroft-Gault formula.Results The mean levels of Cys C,Scr and BUN increased with the decrease of Ccr(P0.05).The ratio of patients with abnormal Cys C and Scr were 56% and 22% in groupⅠ(n=18),77% and 31% in group Ⅱ(n=26) and 100% and 100% in group Ⅲ(n=19),respectively.Conclusion Serum Cys C is a sensitive mark of renal injury.It can be detected easily and effectively used to evaluate the glomerular filtration function as compared with the endogenous creatinine clearane(Ccr) method.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To discuss the value of serum Cystatin C as a sensitive mark in the clinical diagnosis of renal dysfunction and injury.Methods The serum levels of Cys C,Creatinin(Scr) and blood urea nitrogen(BUN) of 63 patients were detected by the immune turbidimetry and enzyme methods.The creantinine clearance(Ccr) was calculated by using Cockcroft-Gault formula.Results The mean levels of Cys C,Scr and BUN increased with the decrease of Ccr(P0.05).The ratio of patients with abnormal Cys C and Scr were 56% and 22% in groupⅠ(n=18),77% and 31% in group Ⅱ(n=26) and 100% and 100% in group Ⅲ(n=19),respectively.Conclusion Serum Cys C is a sensitive mark of renal injury.It can be detected easily and effectively used to evaluate the glomerular filtration function as compared with the endogenous creatinine clearane(Ccr) method.

Key concepts: Medicine, Blood urea nitrogen, Cystatin C, Renal function, Creatinine, Turbidimetry, Internal medicine, Acute kidney injury

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Value of Detecting Serum Cystatin C in Diagnosis of Kidney Disease — Research Paper | ScholarLens