Antioxidative activity of mulberry and its inhibitory effect on tyrosinase

The aim is to measure the antioxidant activity and its inhibitory effect on tyrosinase of three mulberry's extracts.In the study,hydroxyl radicals scavenging activity assay,reducing power assay and lipid peroxidation assay were used,as well as tyrosinase Inhibition test.On the hydroxyl radicals scavenging activity assay,DPPH assay and tyrosinase inhibition test,the antioxidant activity and the inhibitory Effect on tyrosinase of extract in deionized water,in 50% ethanol and in 95% ethanol were shown from high to low.And the IC50 of its water extract in tyrosinase inhibition test is 12.35 mg/mL.On reducing power assay,the antioxidant activity of extract in 50% ethanol was stronger than the extract in deionized water or in 95% ethanol.Otherwise,total flavonoids content of mulberry extracts were 4.11 ~15.84 mg/g.The results show that mulberry has good antioxidative activity and inhibitory effect on tyrosinase.The results could lay good foundation for further studies.