2009•Hainan yixueRequires access
Enteral microecopharmaceutics nutrition in early postoperative patients with advanced gastric cancer
Zhao Xiao-le
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Abstract
Objective To study the clinical effect of enteral microecopharmaceutics nutrition in early postoperative patients with advanced gastric cancer.Methods 60 patients with advanced gastric cancer were randomly divided into two group:enteral microecopharmaceutics nutrition(MEN-group,30 cases),regular enteral natrition group(EN-group,30 cases).Patients were infused with microecopharmaceutics Nutrison Fibre or Nutrison Fibre for 7 postoperative days.The concentrations of endotoxin,TNF and the number of lymphocyte in peripheral blood were analyzed.The changes of S-IgA and microflora in stool were studied.Results The levels of endotoxin and TNF in the MEN group were significantly lower than those in the EN group(P0.01) on 7th day after treatment.The number of lymphocyte in serum was significantly increased after operation in the MEN group while it has no significant alternation in the EN group(P0.05).The amount of S-IgA in stool was markedly increased in the MEN group than that in the EN group(P0.05).Bacterial culture revealed that the amount of bifidobaterium and lactobacilli were notably increased while E.coli.decreased in the MEN group(P0.05).Conclusion The enteral microecopharmaceutics nutrition showed the protective effects on gut barrier function and decreased the postoperation infection rate of patients with advanced gastric cancer.