Relationship between Overweight/Obesity and Fasting Blood Glucose among Different Ethnicities of Uygur,Kazak,Mongolian,Han Ethnical Populations in Xinjiang Boertala Region

Objective To investigate the relationship between overweight/obesity and fasting blood glucose(FBG) among Uygur,Kazak,Mongolian and Han ethnical populations in Xinjiang Boertala region.Methods 3 888 subjects(Uygur 986,Kazak 985,Mongolian 794,Han 1 123)were selected from the cross-sectional study data of metabolism syndrome in Xinjiang Boertala region.Body mass index(BMI) was classified as normal(BMI=18.5 to 23.9 kg/m2),overweight(BMI=24.0 to 27.9 kg/m2) and obesity(BMI≥28.0 kg/m2),and waist circumference(WC) as normal(WCmale 85 cm/female 80 cm),overweight(WC=male 85 to 94 cm/female 80 to 89 cm),abdominal obesity(WC≥male 95 cm/female 90 cm).The FBG levels and the incidence of high FBG among people with different BMI and WC levels were compared,and the relationship between FBG,BMI and WC was analyzed by linear-regression analysis and logistic regression analyses.Results(1) Mean FBG level was(6.1±2.2)mmol/L in Uygur,(5.5±1.2)mmol/L in Kazak,(5.5±1.4)mmol/L in Mongolian,(6.0±2.1)mmol/L in Han,and the difference was statistically significant(F=29.962,P0.001).The average level of FBG and the prevalence rate of high FBG(≥6.1 mmol/L) in Uygur population were significantly increased with the increasing of BMI and WC levels(all P0.05).Mongolian who were overweight or obese had higher FBG levels than the subjects of normal weight(all P0.05).Kazak and Han who were obese or abdominal obese had higher FBG levels than the subjects of normal weight or WC(all P0.05).The prevalence rate of high FBG was not significantly increased with the increasing BMI in Kazak population(P=0.213).(2) After correction confound factors by multiple linear regression,with BMI(from 18.5 to 23.9,24.0 to 27.9 to ≥28 kg/m2) and WC increasing(from WCmale 85 cm/ female 80 cm,male 85~94 cm/female 80~89 cm to ≥male 95 cm/female 90 cm),the level of FBG all increased among the four ethnical populations,and most significantly increased FBG level was Uygur population(respectively B=0.367,0.418,all P0.001),second Mogolian and Han,the last Kazak(respectively β=0.113,0.152,all P0.05).Compared with normal weight or WC level,Uygur population who were overweight(BMI 24.0 to 27.9 kg/m2,WC=male 85 to 94 cm/female 80 to 89 cm)/obesity(BMI≥28 kg/m2,WC≥male 95cm/female 90cm) had the highest risk of high FBG development,but it had no significant influence on Kazak(all P0.05).Compared with normal BMI or WC level,the risk of high FBG development increased among Han who were obesity or abdominal obesity and among Mongolian who were abdominal obesity.Conclusion Among Uygur,Kazak,Mongolian,Han ethnical populations in Xinjiang Boertala region,the influence of increased of BMI or WC on the FBG level and the risk of high FBG development were highest in Uygur,and were lowest in Kazak.