Single Cardiac Cycle Real-time Three-dimensional Echocardiography for Evaluating Right Ventricular Systolic Function of Patients with Atrial Septal Defect

Purpose To assess the right ventricular systolic function and the influence factors before and after treatment of atrial septal defect (ASD) by single cardiac cycle real-time three-dimensional echocardiography (sRT-3DE) in patients with ASD. Materials and Methods Routine examination and sRT-3DE were performed on thirty patients with ASD and thirty normal subjects, and the right ventricular parameters were obtained. The parameter changes was compared and the related influenced factors of right ventricular ejection fraction (RVEF) was analyzed before and after the treatment, and the correlation was evaluated between the RVEF and fraction of area change (FAC). Results The right ventricular end-diastolic volume (RVEDV), the right ventricular end-systolic volume (RVESV), and the right ventricular stroke volume (RVSV) were higher (P0.01), and the RVEF was lower (P0.01) in the ASD group (before treatment) than that in the normal group. After treatment, the RVEDV, RVESV, RVSV in patients with ASD were lower than those before treatment (P0.01), but the RVEF had no significant change (P0.05). RVEF was positively correlated with RVEDV and RVESV (R=0.975, P0.001); RVEF was positively correlated with FAC using sRT-3DE (r=0.792, P0.05). Conclusion sRT-3DE can accurately evaluate the right ventricular contraction of patients with ASD before and after treatment, the decrease of RVEF attributes to the increase of RVESV and RVEDV of ASD.